News Coronavirus Thread

[DaveyBoy123]

Hey! We don’t want to give up our 3 day weekends mate!

Don't make me mutter the words "clever" & "logical" under my breath krakouers. I'm still dirty at you for wanting me to holiday at Rottnest about a week before it became a giant sick bay.

 

[Del191229]

 

[Scallop Industry Thug]

Lol Garrison. ****ing moron.

 

[Scallop Industry Thug]

Brilliant. This is exactly what I was thinking sitting in my seat at marvel a few years back against Adelaide with 4 minutes to play

Someone put Jared Petrenko in enforced quarantine.

 

[Horace]

In my opinion there now needs to be some random sampling of all communities. That might be done using say the Electoral Rolls, by issuing requests to a number of people in various localities, to present for testing. This would not however pick up any information on the level of infection/exposure within those under the age of 18.

For example according to Google just over 16000 people live in Mitcham. If say a request was made of a random sample 1600 or 10% of that population for testing for covid-19, some pretty good results should be achieved. A sample size of 10%, should also be able to provide a pretty good idea of how various age groups are affected.

No doubt this would involve a lot of testing, but it would also give the best idea of just how much the general population has been exposed so far. In my opinion the real worry is no-one really knows how many people, have been in contact with the virus and contracted it but not exhibited any symptoms.

It may also be that, while we are all walking around, eyeing off others, suspicious that they might have it, the reverse could well be true and very few have been in contact and caught the virus. If this was found to be the case, then, it is a nightmare waiting to happen. Open things up again before the virus is actually eradicated, risks another batch of highly vulnerable people to catch it and potentially die.

 

[DesertRoo]

Global stocks rally Friday on Gilead’s coronavirus treatment and Boeing’s production restart

Oil prices drop on Chinese economy contraction

www.foxbusiness.com

Can we go to the pub yet?

Its drug Remdesivir, according to Statnews.com, showed effectiveness for treating COVID-19 patients. Shares of Gilead rose over 10 percent in the extended session.

A recent clinical trial of Remdesivir, an antiviral medicine used as a potential treatment for Ebola, found rapid recoveries in coronavirus patients' fever and respiratory symptoms.

The trial, conducted by the University of Chicago Medicine, found nearly all patients who were given daily infusions of Remdesivir were discharged from the hospital in less than a week.

 

[LuvtheKangas]

Global stocks rally Friday on Gilead’s coronavirus treatment and Boeing’s production restart

Oil prices drop on Chinese economy contraction

www.foxbusiness.com

Can we go to the pub yet?

Its drug Remdesivir, according to Statnews.com, showed effectiveness for treating COVID-19 patients. Shares of Gilead rose over 10 percent in the extended session.

A recent clinical trial of Remdesivir, an antiviral medicine used as a potential treatment for Ebola, found rapid recoveries in coronavirus patients' fever and respiratory symptoms.

The trial, conducted by the University of Chicago Medicine, found nearly all patients who were given daily infusions of Remdesivir were discharged from the hospital in less than a week.

Great news if it proves true, safe and sustainable.

 

[Gasometer]

I wonder if this is what the world felt like in December 1939 with the Phoney War

 

[King Corey]

I wonder if this is what the world felt like in December 1939 with the Phoney War

Telstra vs Optus Phone Wars were in 1996 mate.

 

[Val Keating]

Anyone who wants to hear a reasonable discussion about health V economics should listen to this

#198 — A Conversation with Paul Bloom

Podcast Episode · Making Sense with Sam Harris · 16/04/2020 · 59m

podcasts.apple.com

Give it a go mouncey2franklin

 

[Roogal]

If you get a phone call from North's Membership Department offering to buy in on the Annual Raffle, please try to dig deep if you can afford to or otherwise perhaps offer a small donation to the club. The tickets into the raffle are $200, that's why I suggested that many who may find that too much of a stretch at this point of time may instead offer perhaps a simple $20 donation for the club. Every bit helps. I was able to stump up for a raffle ticket but I also appreciate that while many would like to, it's just not a financial reality.

On the funny side, the girl at the other end of the phone offered a Corporate box for six at Marvel Stadium as the main prize. I did quip back to her that we could have the whole bloody stadium to ourselves ATM. She did say that they would alternatively offer $150,000 cash.

She did say that the club is open but running on reduced staff at Arden Street with many working from home.

 

[Roogal]

Anyone who wants to hear a reasonable discussion about health V economics should listen to this

#198 — A Conversation with Paul Bloom

Podcast Episode · Making Sense with Sam Harris · 16/04/2020 · 59m

podcasts.apple.com

Give it a go mouncey2franklin

There you go ... introducing facts into our ramblings

 

[Val Keating]

[/QUOTE]

There you go ... introducing facts into our ramblings

As much as I’d like to I can’t take credit for just sharing the thoughts of other people

 

[Snake_Baker]

Global stocks rally Friday on Gilead’s coronavirus treatment and Boeing’s production restart

Oil prices drop on Chinese economy contraction

www.foxbusiness.com

Can we go to the pub yet?

Its drug Remdesivir, according to Statnews.com, showed effectiveness for treating COVID-19 patients. Shares of Gilead rose over 10 percent in the extended session.

A recent clinical trial of Remdesivir, an antiviral medicine used as a potential treatment for Ebola, found rapid recoveries in coronavirus patients' fever and respiratory symptoms.

The trial, conducted by the University of Chicago Medicine, found nearly all patients who were given daily infusions of Remdesivir were discharged from the hospital in less than a week.

Great news if it proves true, safe and sustainable.

It's a brilliant little bit of organic chemistry. Remdesivir is designed to slip in to the cellular membrane and it also incorporates a similar structure to the RNA nucleoside adenosine phosphate (the amino acid adenine with a phosphate backbone) which pairs up with viral Uracil in the viral RNA template, and then other functional groups on the compound bring replication to a grinding halt. It basically acts as an unseen saboteur.

Remdesivir



Adenosine monophosphate



Adenine-Uracil RNA bond.

 

[LuvtheKangas]

It's a brilliant little bit of organic chemistry. Remdesivir is designed to slip in to the cellular membrane and it also incorporates a similar structure to the RNA nucleoside adenosine phosphate (the amino acid adenine with a phosphate backbone) which pairs up with viral Uracil in the viral RNA template, and then other functional groups on the compound bring replication to a grinding halt. It basically acts as an unseen saboteur.

Remdesivir

View attachment 859513

Adenosine monophosphate

View attachment 859515

Adenine-Uracil RNA bond.

View attachment 859522

I'd be lying if I said I understood that.

However, I'm pleased that people who have the training and understanding are optimistic about its prospects.

The world would be a better place if people who don't know were more willing to listen to people who do know.

 

[Kangaroos4eva]

 

[Caracas]

It's a brilliant little bit of organic chemistry. Remdesivir is designed to slip in to the cellular membrane and it also incorporates a similar structure to the RNA nucleoside adenosine phosphate (the amino acid adenine with a phosphate backbone) which pairs up with viral Uracil in the viral RNA template, and then other functional groups on the compound bring replication to a grinding halt. It basically acts as an unseen saboteur.

Remdesivir

View attachment 859513

Adenosine monophosphate

View attachment 859515

Adenine-Uracil RNA bond.

View attachment 859522

Lol, Snake. I love it when you make us feel better and more confused- at the same time!


On iPhone using BigFooty.com mobile app

 

[Snake_Baker]

I'd be lying if I said I understood that.

However, I'm pleased that people who have the training and understanding are optimistic about its prospects.

The world would be a better place if people who don't know were more willing to listen to people who do know.

Elements making up compounds exhibiting electrochemical forces that dictate the shape of molecules.

You can conceptually think of the bits and pieces as magnets exhibiting attractive and repulsive forces upon each other and the entire structure, as well as with the other compounds in the vicinity. This is basically how life works. We humans are just complicated membrane bound bags of electrochemical processes.

In this case it's the amine group (NH2) and the accompanying nitrogen molecule (N) next to it on the remdesivir molecule that slip in to the uracil amino acid slot on the viral RNA template (see below), in place of amino acid adenine (NH2 and N) which the virus typically utilises to functionally replicate (go back over the 3 molecule images above and you can see what I mean)

After this occurs, the bulk of the remaining compound of the remdesivir molecule basically throws a spanner in the virals replication works. Think of it like throwing a spanner in to some rolling gears. The other functional groups on remdesivir clog up the replication strand and railroad the viral RNA template = no more virus.

Image: RNA replication, note how C-G (cytosine-guanine) and A-U (adenine-uracil) must align in order to replicate new viral RNA. Interfere with this and the virus does not end up with it's necessary bits & pieces required in order to continue replicating elsewhere (infection).

 

[Snake_Baker]

Lol, Snake. I love it when you make us feel better and more confused- at the same time!


On iPhone using BigFooty.com mobile app

It's all good mate, I try to make this stuff easier for the layperson to pick up.

I am supremely confident that we can put a significant handbrake on the infection aspect of Sars-CoV-2, and slow down it's replication speed, which is really the thing that causes all the issues anyway. Instead of ending up in ICU folks just might end up with a cough at worst until the cavalry arrives (antibodies) and wipes that ****er out altogether. There's no hiding anywhere when that happens. It's over.

 

[spurs]

Elements making up compounds exhibiting electrochemical forces that dictate the shape of molecules.

You can conceptually think of the bits and pieces as magnets exhibiting attractive and repulsive forces upon each other and the entire structure, as well as with the other compounds in the vicinity. This is basically how life works. We humans are just complicated membrane bound bags of electrochemical processes.

In this case it's the amine group (NH2) and the accompanying nitrogen molecule (N) next to it on the remdesivir molecule that slip in to theuracil amino acid on the viral RNA template (see below), in place of amino acid adenine (NH2 and N) which the virus typically utilises to functionally replicate ( go back over the molecule images above and you can see what I mean)

After this occurs, the bulk of the remaining compound of the remdesivir molecule basically throws a spanner in the virals replication works. Think of it like throwing a spanner in to some rolling gears. The other functional groups on remdesivir clog up the replication strand and railroad the viral RNA template = no more virus.

Image: RNA replication, C-G (cytosine-guanine) and A-U (adenine-uracil) must align in order to replicate new viral RNA.

View attachment 859541

Sounds good, but when will it be available to use?

 

[Roogal]

I'd be lying if I said I understood that.

However, I'm pleased that people who have the training and understanding are optimistic about its prospects.

The world would be a better place if people who don't know were more willing to listen to people who do know.

Gezus I can't believe that we didn't all spot it in the first place ... It was so obvious and just sitting there staring us all in the face.

 

[Snake_Baker]

Sounds good, but when will it be available to use?

As far as I know remdesivir was first patented in 2016 and has been utilised with African folks & Ebola.

Based on that this drug should not take long to get a yea or nae.

There's other drugs that have had good results also (hydroxychloroquine)

 

[DaveyBoy123]

Hey gk, is it any better if he corrects a policy on the same day!?

Dan Andrews continues his terrible comms. Yet again he makes a policy today, corrects it tomorrow. The ban on all inspections of homes for sale was never going to stick. So today he back tracks and allows private inspections. I ask again - in terms of PR and Comms, who the hell is advising him because they have stuffed up yet again.

Golfers who had hoped to tee off this weekend had better think again as the game remains officially banned in Victoria. There was a glimmer of hope for desperate golfers after the Department of Health and Human Services advised that golf was not prohibited, and could be played if care was taken.

But in an embarrassing departmental blunder, the advice was wrong after a misunderstanding of a government staffer. It comes as Golf Australia today changed its advice to golf clubs. It had been recommending clubs close but today advised they could open with care.

“Acknowledging the long challenge that lies ahead of all Australians during this pandemic, we have been encouraged to see golf played in comparative safety in five states and one territory in recent weeks as we all adopt social distancing necessities,” it said in a statement.

“Under strict and specific safety protocols – enforced by state and territory guidelines as well as individual club rules – Golf Australia is now satisfied that golf can be played at minimal risk. Having worked collaboratively with our clubs and other stakeholders, we are now comfortable to alter our position and encourage courses to open and for people to play.”

Premier Daniel Andrews has repeatedly urged Victorians to leave the clubs at home. “I’d love to be playing golf. We all would. But I don’t need to play golf, and me playing golf is not worth someone’s life,” he said this morning.

But in what appeared to be an undermining of his position Victoria’s Department of Health and Human Services wrongly advised there was nothing stopping golfers hitting the course. Responding to questions about the state of play, a department staffer advised “golf is not specifically prohibited”. The unidentified staffer, from the COVID-19 Directions Team, said while golf clubs should be encouraging people to stay home, there was nothing stopping play. But golfers had to maintain physical distancing from other people, and only meet with one other person if they are from another household.

Under the government’s tough stay at home restrictions Victorians can leave home for food and supplies, medical care, caregiving, work or study, or basic exercise. “Club members should consider whether golfing is essential exercise,” the DHHS email advised. “In addition, the recommendation for the public is to remain within their immediate neighbourhood to exercise and to only travel out of their neighbourhood if necessary. “Accordingly, golf clubs should be encouraging people to golf locally.”

DHHS advised golf clubs to ensure any shared equipment was thoroughly sanitised, and provide hand sanitiser on the course. It also emphasised people should be staying at home. “The Andrews Government is directing all Victorians to stay at home to help limit the spread of coronavirus (COVID-19). If you can stay home, you must stay home,” the email said.

Victoria’s golf ban has been the subject of anger among keen golfers, with the sport still allowed to be played in other states across the country. AFL great Sam Newman, 74, this week staged a one-man protest at Parliament House over Mr Andrew’s tough stance. “You give me a legitimate reason why golfers can’t socially distance, not touch one another, walk around a golf course, obey the strict rules,” he said. “It is nonsense, there is everyone out on the street jogging, spitting, vomiting. It’s extraordinary. I saw people kicking a football on Olympic Park yesterday, it’s nonsense.”

Shadow sport minister David Hodgett said “most Victorians just want to do the right thing, but draw the line when it comes to limiting healthy activities that pose little risk.” “This is just one of a number of examples of conflicting advice and inconsistency of message between the Premier and Victoria’s Chief Health Officer.”

The Premier has been contacted for comment.

 

[spurs]

As far as I know remdesivir was first patented in 2016 and has been utilised with African folks & Ebola.

Based on that this drug should not take long to get a yea or nae.

There's other drugs that have had good results also (hydroxychloroquine)

Sooooooo....when do you think we will have a vaccine and fuc# this virus off?

 

[Snake_Baker]

Oh FFS mate, ease up!!

Vaccines are already in phase I trials, so they still have to advance past phase II in order to hit the market.

If we can put a handbrake on the thing then a vaccine becomes a moot point anyway. You will make your own vaccine (antibodies)