Play Nice Random Chat Thread IV

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ferball

Premium Platinum
Jul 24, 2015
18,550
35,209
AFL Club
North Melbourne
This is the abstract. I'd like to see the whole thing...

Abstract
Background:
Neuroimaging studies have just begun to explore the acute effects of psychedelics on large-scale brain networks’ functional organization. Even less is known about the neural correlates of subacute effects taking place days after the psychedelic experience. This study explores the subacute changes of primary sensory brain networks and networks supporting higher-order affective and self-referential functions 24 hours after a single session with the psychedelic ayahuasca.

Methods:
We leveraged task-free functional magnetic resonance imaging data 1 day before and 1 day after a randomized placebo-controlled trial exploring the effects of ayahuasca in naïve healthy participants (21 placebo/22 ayahuasca). We derived intra- and inter-network functional connectivity of the salience, default mode, visual, and sensorimotor networks, and assessed post-session connectivity changes between the ayahuasca and placebo groups. Connectivity changes were associated with Hallucinogen Rating Scale scores assessed during the acute effects.
Results:
Our findings revealed increased anterior cingulate cortex connectivity within the salience network, decreased posterior cingulate cortex connectivity within the default mode network, and increased connectivity between the salience and default mode networks 1 day after the session in the ayahuasca group compared to placebo. Connectivity of primary sensory networks did not differ between groups. Salience network connectivity increases correlated with altered somesthesia scores, decreased default mode network connectivity correlated with altered volition scores, and increased salience default mode network connectivity correlated with altered affect scores.

Conclusion:
These findings provide preliminary evidence for subacute functional changes induced by the psychedelic ayahuasca on higher-order cognitive brain networks that support interoceptive, affective, and self-referential functions.
 

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DesertRoo

Norm Smith Medallist
Feb 11, 2013
7,109
13,798
AFL Club
North Melbourne
This is the abstract. I'd like to see the whole thing...

Abstract
Background:
Neuroimaging studies have just begun to explore the acute effects of psychedelics on large-scale brain networks’ functional organization. Even less is known about the neural correlates of subacute effects taking place days after the psychedelic experience. This study explores the subacute changes of primary sensory brain networks and networks supporting higher-order affective and self-referential functions 24 hours after a single session with the psychedelic ayahuasca.

Methods:
We leveraged task-free functional magnetic resonance imaging data 1 day before and 1 day after a randomized placebo-controlled trial exploring the effects of ayahuasca in naïve healthy participants (21 placebo/22 ayahuasca). We derived intra- and inter-network functional connectivity of the salience, default mode, visual, and sensorimotor networks, and assessed post-session connectivity changes between the ayahuasca and placebo groups. Connectivity changes were associated with Hallucinogen Rating Scale scores assessed during the acute effects.
Results:
Our findings revealed increased anterior cingulate cortex connectivity within the salience network, decreased posterior cingulate cortex connectivity within the default mode network, and increased connectivity between the salience and default mode networks 1 day after the session in the ayahuasca group compared to placebo. Connectivity of primary sensory networks did not differ between groups. Salience network connectivity increases correlated with altered somesthesia scores, decreased default mode network connectivity correlated with altered volition scores, and increased salience default mode network connectivity correlated with altered affect scores.

Conclusion:
These findings provide preliminary evidence for subacute functional changes induced by the psychedelic ayahuasca on higher-order cognitive brain networks that support interoceptive, affective, and self-referential functions.
Reading things like this make me happy that I entirely didn’t have a misspent youth but quick question, how can you give a placebo in place of a psychedelic?
surly the control group is sitting there feeling a little ripped off.
 
Last edited:

Snake_Baker

L'enfant terrible
Suspended
Apr 24, 2013
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inside your head
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The Unicornia Reactants
Russel Brand and Yannis Varoufakis
He's on to it.

Now ask yourself this!

Which class pays the most tax, and which demographic benefit from the majority of professional careers from those taxes?

Nothing is going to change in "left wing" Western politics until the workers rise up and take back what is rightfully theirs!!!
 

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goalieboy82

Norm Smith Medallist
Sep 28, 2007
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North Fairfax Kangaroos

andana

Norm Smith Medallist
Feb 1, 2008
7,523
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Thailand
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North Melbourne
This is the sun in Vancouver today. It's all smoke from the fires in the US.

We're also infested with zillions of moths right now, they're all over the place, on people's cars, under your feet on the sidewalk, falling off the trees, they're everywhere. They come inside the vet clinic where I work and pepper the walls before they die. All the little bodies I vacuum up at the end of each day. Covid cases are on the rise again here too, since schools have opened up and restrictions loosened around other activities. So it's pretty much fire, locusts, and plague here right now.

We're still seeing the bulk of our patients outside in the parking lot. We've bought an event tent to put up out there for the Fall. 🌧:cat: ⛺
Such interesting times.

I know it's not always that easy these days, but keep letting the light in, everyone, as much as you can, for yourselves, and for each other. ☀

Peace.

View attachment 960860
You will need to be wearing multiple face masks. Forest fire smoke isn't any good.
 

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