Norm Smith Medallist
- Dec 27, 2017
- AFL Club
- North Melbourne
BTW Tim Dillon has possibly the most offensive podcast available right now...it’s bloody hilarious. Give it a whirl
Reading things like this make me happy that I entirely didn’t have a misspent youth but quick question, how can you give a placebo in place of a psychedelic?This is the abstract. I'd like to see the whole thing...
Neuroimaging studies have just begun to explore the acute effects of psychedelics on large-scale brain networks’ functional organization. Even less is known about the neural correlates of subacute effects taking place days after the psychedelic experience. This study explores the subacute changes of primary sensory brain networks and networks supporting higher-order affective and self-referential functions 24 hours after a single session with the psychedelic ayahuasca.
We leveraged task-free functional magnetic resonance imaging data 1 day before and 1 day after a randomized placebo-controlled trial exploring the effects of ayahuasca in naïve healthy participants (21 placebo/22 ayahuasca). We derived intra- and inter-network functional connectivity of the salience, default mode, visual, and sensorimotor networks, and assessed post-session connectivity changes between the ayahuasca and placebo groups. Connectivity changes were associated with Hallucinogen Rating Scale scores assessed during the acute effects.
Our findings revealed increased anterior cingulate cortex connectivity within the salience network, decreased posterior cingulate cortex connectivity within the default mode network, and increased connectivity between the salience and default mode networks 1 day after the session in the ayahuasca group compared to placebo. Connectivity of primary sensory networks did not differ between groups. Salience network connectivity increases correlated with altered somesthesia scores, decreased default mode network connectivity correlated with altered volition scores, and increased salience default mode network connectivity correlated with altered affect scores.
These findings provide preliminary evidence for subacute functional changes induced by the psychedelic ayahuasca on higher-order cognitive brain networks that support interoceptive, affective, and self-referential functions.
He's on to it.Russel Brand and Yannis Varoufakis
maybe as a mini series (like they might be doing with the Dambusters)80 years ago woah
Deserves a new movie version
You will need to be wearing multiple face masks. Forest fire smoke isn't any good.This is the sun in Vancouver today. It's all smoke from the fires in the US.
We're also infested with zillions of moths right now, they're all over the place, on people's cars, under your feet on the sidewalk, falling off the trees, they're everywhere. They come inside the vet clinic where I work and pepper the walls before they die. All the little bodies I vacuum up at the end of each day. Covid cases are on the rise again here too, since schools have opened up and restrictions loosened around other activities. So it's pretty much fire, locusts, and plague here right now.
We're still seeing the bulk of our patients outside in the parking lot. We've bought an event tent to put up out there for the Fall.
Such interesting times.
I know it's not always that easy these days, but keep letting the light in, everyone, as much as you can, for yourselves, and for each other.
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