Even the random enemies in this game make you stop and think sometimes. Someone on Reddit posted a pictured of them sniping down at a raider, only to notice the raider was mourning someone at a grave site. These enemies you mercilessly mow down are people too!
Super mutants even pose interesting thoughts. First example I can think of was when a super mutant ran at me screaming "You've had your time". He's not wrong, humans did ruin the planet. Maybe the mutants would do a better job? Next example was when one yelled out during fighting "You humans made us, now you must deal with the consequences". Again, fair point.