lemme guess... the harpoon gun?Finally got through the 5th biome after about 5 or 6 game crashes on runs where i'd been doing well. Had 2 back up lives and about halfway through the 6th biome I decide to pick up a new weapon i'd never used. What an awful mistake. Immediately in a fight against two tough enemies plus a bunch of smaller annoying enemies and I have a gun i've never used that has no power ups, lose one life, try to run away, end up at a dead end, go back, lose next life so go back to that reanimator thing. Thankfully got to trace my steps back and get the awesome tachyomatic carbine I had in the first place. Continue on, get to the boss, get it to it's last health bar and die.
I have such deep regrets about picking up that weapon. Deep, deep regrets. I had 200% health, 40% protection, things were going so well