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strikethru codeFind it hard to believelifecan get to that point
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strikethru codeFind it hard to believelifecan get to that point
but, i dont think poseidon's opinion hurts if you are successful.
irony is, it actually causes more grief to the suicide's family. in terms of its logic and argument, its a fail.
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prozac longer half life than its successors in ssri family.Lots of interesting discussion here. Just to add my two cents, the interesting thing about anti-depressants such as selective serotonin reuptake inhibitors (SSRIs or Prozac for example), is that the original mechanism through which they were proposed to work is the subject of intense research/scrutiny. In very simple terms, drugs like Prozac increase the "availability" of serotonin (a neurotransmitter which causes elevated mood in higher concentrations) in the synaptic cleft by, as the name would suggest, reducing the uptake of the neurotransmitter molecules back into the synapse, leading to the aforementioned higher concentrations acting upon our chemical neuronal signalling.
This works in many cases, but studies have shown that it takes upwards of a month for there to be any noticeable difference in brain serotonin levels, whereas people will typically experience more immediate relief upon their first course of medication. This obviously presents questions over the mechanisms of their efficacy (and it should be noted that they aren't a 100% sure fire "cure"). Someone with a more pharmacological background will probably be able to provide further info on the latest developments in anti-depressant research, as I'm certainly no expert.
From experience/teaching, new wave SSRIs are typically the first port of call, and are good for those who are critically depressed, but less so for milder forms of depression. Drugs can be an excellent treatment source, but fail to address any personal and cognitive factors that often underlie depressive episodes that present an underlying vulnerability to relapse. My suggestion would be to keep an open mind to both psychopharmacology and psychotherapy. Psychiatrists and psychologists alike are great outlets for finding help, and remember that this help is always available.
prozac longer half life than its successors in ssri family.
i thought the recent material on theory surrounding ssri is that the reverse engineering theory of the seratonin is no longer the influential element. then again i would only have come across it from a second source like the medical journalist on abc.(who is a doc tho)
Yeh in all honesty there is so much being done on the biological underpinnings of depression that it's hard to separate the wood from the trees. Like I said, you may well be right in that the prevailing theory of is mechanism of action has shifted, but it's my understanding that the overall monoamine hypothesis (i.e. chemical disruptions as the biological core) remains. This isn't exclusive to just serotonin too, norepinephrine and dopamine have also been implicated, hence the use of other drugs like tricyclic anti-depressants and MOA inhibitors.
How do we know this?Suicide is absolutely tragic for those who have died
Suicide is one method of avoiding being disturbed and disgusted.You live once, make the most of it.
That's how I see it, suicide is a disturbing and disgusting thing.
I'm so sorry to hear about your friend NickyThat's rubbish.
a friend of mine recently committed suicide and i'm heartbroken about how much pain she was in and how long she held on for even though she was suffering so much. This life was a living hell for her and not in a "i'm depressed" kind of way. It was torture. Anyone insisting someone continue to live through that because they don't want to say goodbye or confront their own mortality is the true selfish one.

I'm sure that this uncertainty about the efficacy of various drugs will be sorted out well before we run out of human guinea pigs to test them on. It's all in the fine-tuning.
Research I read on neuroplasty is fascinating. Whilst I grasp the basics of what I read I dont fully appreciate all of the medical terms and significance of the results so far.
The jist of it is that the long held belief that the mind functions as a direct result of the physical make up of the brain is being challenged. The established belief is that the mind has no influence over the brain and can not affect it in any way and that the mind is a product of a persons brain.
Neuroplasty is challenging that belief and that the mind can in fact alter the brain and can change its physical structures or neural structures/connections. Meditation is proving to be useful in creating new neural pathways within the brain that can help people with mood disorders, depression and even habitual behaviours like self harming. Its proving to be useful for some stroke victims in assisting them to regain functionality that was previously considered permanently lost. There are various techniques that can help create new pathways in the brain too depending on what function is needed.
I should read more about.
I'm sure that this uncertainty about the efficacy of various drugs will be sorted out well before we run out of human guinea pigs to test them on. It's all in the fine-tuning.
I'm so sorry to hear about your friend Nicky![]()
still doing ECT too, even tho it has got a bad name in popular press. it immediately rouses connotations of kew cottages and early C20 sanitoria (think thats the plural of sanitorium) tho i dont think it is a treatment for long-term patientsI would like to echo the importance of seeking help if you need it. It is available, and you may find something that works for you. It could be psychotherapy, CBT, medication, some other form of therapy or a combination, the fact is these methods have worked in the past on people in similar conditions.
still doing ECT too, even tho it has got a bad name in popular press. it immediately rouses connotations of kew cottages and early C20 sanitoria (think thats the plural of sanitorium) tho i dont think it is a treatment for long-term patients
How do we know this?
but not a regimen for long term depressives, psychoanalysis/psychotherapthy, CBT and pharmaceuticals, then again, i am a laypersonKen Kesey has a bit to answer for, ECT actually has a very good side-effect profile, comparatively
What shocks me about some medications is that when a patient comes off of medication they can often end up feeling worse than they did before they went on them. Lithium is a prime example of this.
Skilts is just pointing out the flaw in the logic , aint a big believer in jung and freudHow do we know what? That the grief associated with suicide for those killing themselves/attemping to and those left behind is painful and immense? I think it's pretty obvious.
What are you chasing here? A scientific answer?
With whom among the dead have you spoken, allowing you to come to the conclusion that the experience was "absolutely tragic for those who have died"?How do we know what? That the grief associated with suicide for those killing themselves/attemping to and those left behind is painful and immense? I think it's pretty obvious.
What are you chasing here? A scientific answer?
With whom among the dead have you spoken, allowing you to come to the conclusion that the experience was "absolutely tragic for those who have died"?