On the assumption that he is a must-have defender and you will have to get him at some stage, why not just start with him and save a trade?
Just because you will want him in your final team, doesnt mean that starting with him is saving you a trade.
For example, if he downgraded goddard to a 350k player (ie still a keeper) and used the extra 100k or so to go from a Dangerfield to a Gray (another keeper) or a McVeigh to Ball/Mclean (another keeper) then he has effectively 2 keepers there, when you would only have one with the alternative combo that includes goddard.
Another example:
(Mid pricer + Mid pricer) v (Premium + Rookie)
By your logic, I should go option 2, as starting with the premium will "save me a trade". However, it will take 2 trades to upgrade the rookie, and thus 2 trades to get two premiums/keepers for option 2. Alternatively, the mid pricers in option 1 will only need one trade each, meaning that two keepers/premiums can again be gained through 2 trades. Thus, no trade is saved.
Food for thought.