Play Nice Random Chat Thread: Episode III

[Snake_Baker]

Tourists should be told when they get here “Pretty everything can kill you, have a nice stay”

We're overdue for the annual picture of a septic standing waist deep in the Daly River.

 

[Snake_Baker]

 

[King Corey]

Balls of Steel was a great show. Bunny Boiler, Alex Zane etc. I'm told there was an Australian version that was somewhat less amusing...

Actually I think it's time for some Alex Zane right now-

 

[King Corey]

It doesn't take the intervention of a football club to know that sticking up for your mates is right.

The NMFC is no holier than thou social conditioning unit, it's a football club.................or at least it used to be.

Fwiw this is the North Melbourne new player induction opening statement:

Our mission is to help you develop important skills that will support both your private and professional lives, refining you into an elegant lady or confident business executive that will help you achieve your social endeavours, seek overseas investors, or make an impression at a job or university interview. In today’s increasingly global society, international etiquette is an essential resource that often determines who becomes a leader, and who gets left behind. We could say it is your passport to feeling at ease in any situation – from effortlessly navigating the place setting of a formal meal to correctly greeting and entertaining VIP Clients.​

Strangely it's identical to the Australian Finishing School's mission statement but that's because these types of organisations are so closely aligned these days.

 

[Snake_Baker]

Social Cohesion: Social Marketing Campaign against hate

The Huddle, City of Wyndham, the City of Whittlesea and the Centre for Multicultural Youth all teamed up together to deliver an innovative project where young people took the lead in a social marketing campaign against hate and racism and to promote social cohesion. Young people were guided, mentored and equipped with the skills to facilitate and launch these campaigns through social-marketing.

This initiative aimed to engage young people in a unique, innovative and exciting anti-racism/positive social cohesion campaign. The multi-faceted and cross-organisational venture aimed to empower young people to be able to:
• Take a stand against hate and racism
• Collectively launch and steer a major social marketing scheme
• Actively take part in an integrated communications campaign
• Use contemporary marketing based methodologies to tackle an issue of social significance
• Help prevent radicalisation and violent extremism


• Build resilience to prevent hate speech
• Empower them to create positive & constructive dialogue in their community
• Strengthen relationships between young people
• Highlight role they play in creating social cohesion in our community
• Increase the understanding of marginalised people
• Increase the inclusion of marginalised people
• Increase the trust in local community members
• Increase value of diversity & resilience




It's ****ing disturbing.

I don't remember standing on the steps of the Dallas Brooks Hall because of any of this crap.

 

[Groin guru]

Balls of Steel was a great show. Bunny Boiler, Alex Zane etc. I'm told there was an Australian version that was somewhat less amusing...

Actually I think it's time for some Alex Zane right now-

Yep. Australian version wasn't as funny. Neg was in it and had some funny scenes like throwing pizza and chips at people. There was one other character that was good. Bunny boiler copped some flack at the time from memory because I think she actually broke a married couple up

 

[Snake_Baker]

 

[Twinkletoes]

Yep. Australian version wasn't as funny. Neg was in it and had some funny scenes like throwing pizza and chips at people. There was one other character that was good. Bunny boiler copped some flack at the time from memory because I think she actually broke a married couple up

The only thing going for the Aussie version was The Nude Twins.

 

[ferball]

Social Cohesion: Social Marketing Campaign against hate

The Huddle, City of Wyndham, the City of Whittlesea and the Centre for Multicultural Youth all teamed up together to deliver an innovative project where young people took the lead in a social marketing campaign against hate and racism and to promote social cohesion. Young people were guided, mentored and equipped with the skills to facilitate and launch these campaigns through social-marketing.

This initiative aimed to engage young people in a unique, innovative and exciting anti-racism/positive social cohesion campaign. The multi-faceted and cross-organisational venture aimed to empower young people to be able to:
• Take a stand against hate and racism
• Collectively launch and steer a major social marketing scheme
• Actively take part in an integrated communications campaign
• Use contemporary marketing based methodologies to tackle an issue of social significance
• Help prevent radicalisation and violent extremism


• Build resilience to prevent hate speech
• Empower them to create positive & constructive dialogue in their community
• Strengthen relationships between young people
• Highlight role they play in creating social cohesion in our community
• Increase the understanding of marginalised people
• Increase the inclusion of marginalised people
• Increase the trust in local community members
• Increase value of diversity & resilience




It's ****ing disturbing.

I don't remember standing on the steps of the Dallas Brooks Hall because of any of this crap.

Why do you think its a bad thing?

How does it hurt the club?

Frankly if Hooter has worked out that not putting dickheads in hospital is better than going ballistic and losing control of yourself because of his time at North that is a good thing. If he's learned that for whatever reason its a good thing.

 

[Snake_Baker]

Why do you think its a bad thing?

The absurd politics that guides it.

How does it hurt the club?

It detracts from football, and we are a football club.

Frankly if Hooter has worked out that not putting dickheads in hospital is better than going ballistic and losing control of yourself because of his time at North that is a good thing. If he's learned that for whatever reason its a good thing.

He could have knocked out the antagonist and stil be in the right, according to my thinking.

 

[Snake_Baker]

I normally keep my science & medical ranting in the science board, but this is too important not to share here:

A cure for cancer? Israeli scientists say they think they found one

“We believe we will offer in a year's time a complete cure for cancer."

By Maayan Jaffe-Hoffman

January 28, 2019 23:14

A small team of Israeli scientists think they might have found the first complete cure for cancer.

“We believe we will offer in a year’s time a complete cure for cancer,” said Dan Aridor, of a new treatment being developed by his company, Accelerated Evolution Biotechnologies Ltd. (AEBi), which was founded in 2000 in the ITEK incubator in the Weizmann Science Park. AEBi developed the SoAP platform, which provides functional leads to very difficult targets.

“Our cancer cure will be effective from day one, will last a duration of a few weeks and will have no or minimal side-effects at a much lower cost than most other treatments on the market,” Aridor said. “Our solution will be both generic and personal.”

It sounds fantastical, especially considering that an estimated 18.1 million new cancer cases are diagnosed worldwide each year, according to reports by the International Agency for Research on Cancer. Further, every sixth death in the world is due to cancer, making it the second leading cause of death (second only to cardiovascular disease).

Aridor, chairman of the board of AEBi and CEO Dr. Ilan Morad, say their treatment, which they call MuTaTo (multi-target toxin) is essentially on the scale of a cancer antibiotic – a disruption technology of the highest order.

The potentially game-changing anti-cancer drug is based on SoAP technology, which belongs to the phage display group of technologies. It involves the introduction of DNA coding for a protein, such as an antibody, into a bacteriophage – a virus that infects bacteria. That protein is then displayed on the surface of the phage. Researchers can use these protein-displaying phages to screen for interactions with other proteins, DNA sequences and small molecules.

In 2018, a team of scientists won the Nobel Prize for their work on phage display in the directed evolution of new proteins – in particular, for the production of antibody therapeutics.

AEBi is doing something similar but with peptides, compounds of two or more amino acids linked in a chain. According to Morad, peptides have several advantages over antibodies, including that they are smaller, cheaper, and easier to produce and regulate.

When the company first started, Morad said, “We were doing what everyone else was doing, trying to discover individual novel peptides for specific cancers.” But shortly thereafter, Morad and his colleague, Dr. Hanan Itzhaki, decided they wanted to do something bigger.

To get started, Morad said they had to identify why other cancer-killing drugs and treatments don’t work or eventually fail. Then, they found a way to counter that effect.

For starters, most anti-cancer drugs attack a specific target on or in the cancer cell, he explained. Inhibiting the target usually affects a physiological pathway that promotes cancer. Mutations in the targets – or downstream in their physiological pathways – could make the targets not relevant to the cancer nature of the cell, and hence the drug attacking it is rendered ineffective.

In contrast, MuTaTo is using a combination of several cancer-targeting peptides for each cancer cell at the same time, combined with a strong peptide toxin that would kill cancer cells specifically. By using at least three targeting peptides on the same structure with a strong toxin, Morad said, “we made sure that the treatment will not be affected by mutations; cancer cells can mutate in such a way that targeted receptors are dropped by the cancer.”

“The probability of having multiple mutations that would modify all targeted receptors simultaneously decreases dramatically with the number of targets used,” Morad continued. “Instead of attacking receptors one at a time, we attack receptors three at a time – not even cancer can mutate three receptors at the same time.”

Furthermore, many cancer cells activate detoxification mechanisms when in stress from drugs. The cells pump out the drugs or modify them to be non-functional. But Morad said detoxification takes time. When the toxin is strong, it has a high probability of killing the cancer cell before detoxification occurs, which is what he is banking on.

https://www.jpost.com/HEALTH-SCIENC...ientists-say-they-think-they-found-one-578939

 

[Snake_Baker]

Phage technology:

 

[king of the road]

Social Cohesion: Social Marketing Campaign against hate

The Huddle, City of Wyndham, the City of Whittlesea and the Centre for Multicultural Youth all teamed up together to deliver an innovative project where young people took the lead in a social marketing campaign against hate and racism and to promote social cohesion. Young people were guided, mentored and equipped with the skills to facilitate and launch these campaigns through social-marketing.

This initiative aimed to engage young people in a unique, innovative and exciting anti-racism/positive social cohesion campaign. The multi-faceted and cross-organisational venture aimed to empower young people to be able to:
• Take a stand against hate and racism
• Collectively launch and steer a major social marketing scheme
• Actively take part in an integrated communications campaign
• Use contemporary marketing based methodologies to tackle an issue of social significance
• Help prevent radicalisation and violent extremism


• Build resilience to prevent hate speech
• Empower them to create positive & constructive dialogue in their community
• Strengthen relationships between young people
• Highlight role they play in creating social cohesion in our community
• Increase the understanding of marginalised people
• Increase the inclusion of marginalised people
• Increase the trust in local community members
• Increase value of diversity & resilience




It's ****ing disturbing.

I don't remember standing on the steps of the Dallas Brooks Hall because of any of this crap.

Awesome. Snake turns another thread into a soap box for a political rant that bears no relation to the actual thread topic.

What does Marley Williams being associated with a pub fight have to do with the Huddle? (That’s a rhetorical question - because pretty much all of us know the answer - NOTHING!!!)

Your footy analysis can be good Snake. But your relentless pursuit of political agendas is overbearing. Stick to the thread topics or make a new one called ‘Snakes right wing political axe to grind thread’. Then Nth fans can connect on the issues on the thread title instead of mistakenly believing they’ve clicked on an Andrew Bolt article every time we get on BF.

 

[Firestarter]

Awesome. Snake turns another thread into a soap box for a political rant that bears no relation to the actual thread topic.

What does Marley Williams being associated with a pub fight have to do with the Huddle? (That’s a rhetorical question - because pretty much all of us know the answer - NOTHING!!!)

Your footy analysis can be good Snake. But your relentless pursuit of political agendas is overbearing. Stick to the thread topics or make a new one called ‘Snakes right wing political axe to grind thread’. Then Nth fans can connect on the issues on the thread title instead of mistakenly believing they’ve clicked on an Andrew Bolt article every time we get on BF.

He hates political soapboxing so much that he does it to beat everyone to the punch.

 

[Snake_Baker]

Awesome. Snake turns another thread into a soap box for a political rant that bears no relation to the actual thread topic.

What does Marley Williams being associated with a pub fight have to do with the Huddle? (That’s a rhetorical question - because pretty much all of us know the answer - NOTHING!!!)

Your footy analysis can be good Snake. But your relentless pursuit of political agendas is overbearing. Stick to the thread topics or make a new one called ‘Snakes right wing political axe to grind thread’. Then Nth fans can connect on the issues on the thread title instead of mistakenly believing they’ve clicked on an Andrew Bolt article every time we get on BF.

I am not "pursuing political agendas", I am highlighting the people who have set up shop inside the club to "pursue political agendas"

He hates political soapboxing so much that he does it to beat everyone to the punch.

See, you people aren't questioning my content, you are questioning my right to even express that content. You simply want to shut down all opposing views.

I was actually responding to a sarcastic observation of a moderator, but I can see how you would just overlook that and head straight to me.

Clearly, this stuff, which is a real part of the club at the moment, and therefore worthy of discussion, conflicts with your world view.

Well, bad luck. This place does not exist to censor opposition to your club/political world view. Provide rebuttal or just skip by the thing.

I scroll past lots of stuff I can't be bothered with, and it's not as if recent discussion of Marley Williams in this thread has been about his football.

 

[Sopwiths North]

It doesn't take the intervention of a football club to know that sticking up for your mates is right.

The NMFC is no holier than thou social conditioning unit, it's a football club.................or at least it used to be.

"Holier than thou"? I never said that. And yes, it IS a football club. Which chooses to invest itself in the well-being of its players. Well-being meaning encompassing all aspects of personal development. Why you insist on thinking that the two must be mutually exclusive, or that a more wholistic approach to developing players somehow constitutes a political agenda is beyond me. But then fear does weird stuff to people's minds.

Also not sure why you brought up The Huddle, but since you did, here's more scariness. Watch at your own peril. (Or don't. Your decision.)






"Most of all, we appreciate our young people. Bright, hardworking, resilient, and strong, who attend The Huddle every day, and are open to teach, learn, grow, and help one another."

Really struggle to understand why this stuff incenses you so much. But hey, to each his own.

 

[Snake_Baker]

Some of the better waffle I have read around here.

 

[big_e]

 

[Firestarter]

Are we allowed think-speak yet?

 

[big_e]

Are we allowed think-speak yet?

Dunno. I'll ask Snake_Baker

 

[Snake_Baker]

Dunno. I'll ask Snake_Baker

Bit of a silly thing to ask card carrying anarchist

 

[Firestarter]

And I'm a card carrying arsonist.

 

[Tas]

I normally keep my science & medical ranting in the science board, but this is too important not to share here:

A cure for cancer? Israeli scientists say they think they found one

“We believe we will offer in a year's time a complete cure for cancer."

By Maayan Jaffe-Hoffman

January 28, 2019 23:14

A small team of Israeli scientists think they might have found the first complete cure for cancer.

“We believe we will offer in a year’s time a complete cure for cancer,” said Dan Aridor, of a new treatment being developed by his company, Accelerated Evolution Biotechnologies Ltd. (AEBi), which was founded in 2000 in the ITEK incubator in the Weizmann Science Park. AEBi developed the SoAP platform, which provides functional leads to very difficult targets.

“Our cancer cure will be effective from day one, will last a duration of a few weeks and will have no or minimal side-effects at a much lower cost than most other treatments on the market,” Aridor said. “Our solution will be both generic and personal.”

It sounds fantastical, especially considering that an estimated 18.1 million new cancer cases are diagnosed worldwide each year, according to reports by the International Agency for Research on Cancer. Further, every sixth death in the world is due to cancer, making it the second leading cause of death (second only to cardiovascular disease).

Aridor, chairman of the board of AEBi and CEO Dr. Ilan Morad, say their treatment, which they call MuTaTo (multi-target toxin) is essentially on the scale of a cancer antibiotic – a disruption technology of the highest order.

The potentially game-changing anti-cancer drug is based on SoAP technology, which belongs to the phage display group of technologies. It involves the introduction of DNA coding for a protein, such as an antibody, into a bacteriophage – a virus that infects bacteria. That protein is then displayed on the surface of the phage. Researchers can use these protein-displaying phages to screen for interactions with other proteins, DNA sequences and small molecules.

In 2018, a team of scientists won the Nobel Prize for their work on phage display in the directed evolution of new proteins – in particular, for the production of antibody therapeutics.

AEBi is doing something similar but with peptides, compounds of two or more amino acids linked in a chain. According to Morad, peptides have several advantages over antibodies, including that they are smaller, cheaper, and easier to produce and regulate.

When the company first started, Morad said, “We were doing what everyone else was doing, trying to discover individual novel peptides for specific cancers.” But shortly thereafter, Morad and his colleague, Dr. Hanan Itzhaki, decided they wanted to do something bigger.

To get started, Morad said they had to identify why other cancer-killing drugs and treatments don’t work or eventually fail. Then, they found a way to counter that effect.

For starters, most anti-cancer drugs attack a specific target on or in the cancer cell, he explained. Inhibiting the target usually affects a physiological pathway that promotes cancer. Mutations in the targets – or downstream in their physiological pathways – could make the targets not relevant to the cancer nature of the cell, and hence the drug attacking it is rendered ineffective.

In contrast, MuTaTo is using a combination of several cancer-targeting peptides for each cancer cell at the same time, combined with a strong peptide toxin that would kill cancer cells specifically. By using at least three targeting peptides on the same structure with a strong toxin, Morad said, “we made sure that the treatment will not be affected by mutations; cancer cells can mutate in such a way that targeted receptors are dropped by the cancer.”

“The probability of having multiple mutations that would modify all targeted receptors simultaneously decreases dramatically with the number of targets used,” Morad continued. “Instead of attacking receptors one at a time, we attack receptors three at a time – not even cancer can mutate three receptors at the same time.”

Furthermore, many cancer cells activate detoxification mechanisms when in stress from drugs. The cells pump out the drugs or modify them to be non-functional. But Morad said detoxification takes time. When the toxin is strong, it has a high probability of killing the cancer cell before detoxification occurs, which is what he is banking on.

https://www.jpost.com/HEALTH-SCIENC...ientists-say-they-think-they-found-one-578939

I hope this comes out before I get Dude Arse Cancer.

 

[Tas]

Robbie's brother hasn't aged well. Bad genes.

 

[Firestarter]

Robbie's brother hasn't aged well. Bad genes.

He's now related to a Pom. F.